
SS-31 10mg
SS-31 (Elamipretide)
CAS: 736992-21-5
SS-31 (Elamipretide, MTP-131) is a mitochondria-targeted tetrapeptide that binds cardiolipin in the inner mitochondrial membrane. Restores ATP synthesis in aged and ischemic models. Phase 2 clinical data in heart failure and Barth syndrome. 98.9% HPLC purity.
Specifications
For laboratory research use only. Not for human consumption.
Mechanism of Action
Cardiolipin stabilization in the inner mitochondrial membrane preserves electron transport chain supercomplex organization (Complex I/III/IV), reducing electron leak, ROS generation, and restoring ATP production efficiency.
Research FAQ
What is the mechanism of SS-31 in aging research?
Mitochondrial dysfunction in aging involves cardiolipin oxidation that disrupts electron transport chain supercomplexes. SS-31 binds and protects cardiolipin, reversing this dysfunction to restore ATP output in aged cell models.
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Water for Injection, 0.9% Benzyl Alcohol